Alcohol and longevity: Difference between revisions

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Latest revision as of 01:05, 7 June 2024

The general conclusion is that alcohol in moderate doses has no effect on longevity.

https://pubmed.ncbi.nlm.nih.gov/20941640/ 1.34 mln Koreans
No difference in all-cause mortality between 1-15g/day and 15-30g/day (table 3, p.5)
Correspondingly, RR = 0.87 (0.84–0.91), and RR = 0.88 (0.84–0.92)
In table 5 for men, even correspondingly RR = 0.81 (0.75–0.87) and RR = 0.79 (0.72–0.88)
btw, 30g ethanol is 38ml ethanol (ethanol density is 0.789g/ml) which is 380ml wine (10% ethanol)

https://pubmed.ncbi.nlm.nih.gov/26997174/
table 2 (p.8), 1.3-25g ethanol/day RR 1.02 (0.95-1.10) compared to <1.3g ethanol/day
table 3 is similar
table 4 -- in all cases 1.3-25g was better than <1.3g
Even in Fig.3 after removing biases, still occasional drinking (<1.3g/day) was better than abstaining from alcohol.
Only when they from 81 papers took 13 papers without abstainer biases, and moreover took 6 "the best" from them, only then they get (statistically insignificant) increase of all-cause mortality for 1.3 - 25 (!) g ethanol/day (Fig.4).
Authors write: "in all the pooled models presented, regardless of whether outliers were excluded or studylevel characteristics were controlled for, occasional drinkers had very similar mortality risks to low-volume drinkers". By occasional they mean <1.3g/day, by low-volume 1.3 - 25 (!) g ethanol/day.

Sometimes the harm of moderate alcohol consumption is justified with article https://pubmed.ncbi.nlm.nih.gov/30146330/
However it's possibly wrong for the following reasons: Review on 30146330